A class of compounds targeting FAK, labels, and preparation methods and applications of compounds and labels

The present invention provides a class of compounds targeting FAK, wherein the structure is represented by the following formula (I), X is an N atom or a Cl-substituted C atom, R1 is -OH, -O-CH2-CH2-OH or -O-CH2-CH2-F, and R2 is methylamino or dimethylamino. The present invention further provides a class of radioactively labeled compounds targeting FAK. According to the present invention, the compounds have excellent in vitro FAK kinase activity inhibition effects, and the radioactive labels have ideal biodistribution in rice bearing S180 tumor. The present invention further provides preparation methods of the compounds and the radioactive labels, and applications in preparation of antitumor drugs. The formula (I) is defined in the specification.