Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embryos

Zhiren Zhang,Yanhui Zhai,Xiaoling Ma,Sheng Zhang,Xinglan An,Hao Yu,Ziyi Li

Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embryos

2018

Zhiren Zhang
Yanhui Zhai
Xiaoling Ma
Sheng Zhang
Xinglan An
Hao Yu
Ziyi Li

Background/Aims: Aberrantly high levels of H3K4me3, caused by incomplete epigenetic reprogramming, likely cause a low efficiency of somatic cell nuclear transfer

Keywords:

Reprogramming
Biochemistry
H3K4me3
Cell biology
Somatic cell nuclear transfer
Embryo
Downregulation and upregulation
Biology
Epigenetics
Regulation of gene expression
Blastocyst
Gene expression
Histone methyltransferase

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