Iodinated cyanine dyes: a new class of sensitisers for use in NIR activated photodynamic therapy (PDT)

Jordan Atchison,Sukanta Kamila,Heather Nesbitt,Kieran Logan,Dean Nicholas,Colin Fowley,James Davis,Bridgeen Callan,Anthony McHale,John F. Callan

Iodinated cyanine dyes: a new class of sensitisers for use in NIR activated photodynamic therapy (PDT)

2017

Jordan Atchison
Sukanta Kamila
Heather Nesbitt
Kieran Logan
Dean Nicholas
Colin Fowley
James Davis
Bridgeen Callan
Anthony McHale
John F. Callan

A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in two pancreatic cell lines as well as excellent tumour control in a murine model of the disease.

Keywords:

Photodynamic therapy
Organic chemistry
Cyanine
Photochemistry
Chemistry
murine model
Pancreatic cancer

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