Comparative Studies on the Effects of Interleukin-4 and Interleukin-13 on Cytokine and Prostaglandin E2 Production by Amnion-derived WISH Cells

PROBLEM: In hematopoietic cells, interleukin (IL)-13 shares many actions with IL-4. The effects of IL-13 in gestational tissues have yet to be reported, however. We compared the effects of IL-4 and IL-13 on the production of cytokines and prostaglandin E-2 (PGE(2)) in epithelial amnion-derived WISH cells.