Antibacterial Components from Dragon' s Blood of Dracaena cambodiana

Objective To study the chemical constituents of the ethanol extract from the dragon's blood in Dracaena cambodiana Pierre ex Gagnep.Methods Silica gel and sephadex LH-20 colunm chromatography were employed for the isolation and purification.The structures of compounds were elucidated by the physico-chemical properties and spectral analyses.Results 8 compounds were identified as follows:1-hydroxy-6,8-dimethoxy-3-methylanthracene-9,10-dione(1),diosgenin(2),pennogenin(3),sinapaldehyde(4),3,4,2',4'-tetrahydroxy-3'-methoxychalcone(5),2',4',4-trihydroxy-3-methoxychalcone(6),epipinoresinol(7),and(3E)-2,3-dihydro-7-hydroxy-3-[(3-hydroxy-4-methoxyphenyl)-methylene]-4H-1-benzopyran-4-one(8),respectively.Conclusion Compounds 1 ~ 8 were isolated from dragon's blood of D.cambodiana for the first time.Compounds 2 ~ 7 have inhibitory effect on Staphylococcu aureus(SA).