Evaluation of Analgesic and Antipyretic activity of Marsilea trifolia Blanco

The main aim of this study was to find out the Antipyretic and analgesic effects of Marsilea trifolia Blanco (Family: Marsilea- ceae) fresh leaf aqueous extract, a Bangladeshi medicinal plant. The extract exhibited marked analgesic effect by reduction of writhings inducted by acetic acid at dose of 100, 200 and 300mg/kg (p.o) in mice. Analgesic effect was also observed with the hot plate device main- tained at 55°C. Moreover, the extract produced a significant inhibition (P<0,01) in yeast induced pyrexia in rats. This study confirms tradi- tional use of Marsilea trifolia Blanco as remedy for fever.