Synthesis of spacered derivatives of β-lactosylamine with an amino function at the terminal position of an aglycon

A set of N-acyllactosylamine derivatives containing a terminal amino group in aglycons of various lengths (up to 16 atoms) and various hydrophilicities were synthesized. The aglycons were represented by di-, tri-, and pentapeptides containing glycine and serine residues and by aglycons containing fragments of tartaric acid or a tertiary amine.