Sustained benefit of left ventricular remodelling after valve replacement for aortic stenosis
2009
Background: Valve replacement for aortic stenosis (AS) determines negative ventricular
remodelling. We used cross sectional and Doppler echocardiography to check how rapidly it occurs and to assess if these changes are sustained over time.
Methods: We evaluated in 34 patients subjected to aortic valve replacement for AS morphological
and functional (ejection fraction and E:A ratio) left ventricular data by echocardiography
prior to surgery and 2 postoperative studies: early after surgery (pQ1) and at
mid-term evolution (pQ2).
Results: Left ventricular mass index was reduced at pQ1 (from 152 ± 47 g/m 2 to 113 ± 31 g/m 2 ;
p Conclusions: Aortic valve replacement surgery leads to a rapid negative left ventricular
remodelling during the first 7 months, including a decrease in myocardial hypertrophy and an
improvement in systolic and diastolic function. These beneficial hemodynamic changes are
sustained for at least 3 years.
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