Abi1 loss drives prostate tumorigenesis through activation of EMT and noncanonical WNT signaling.

Disharee Nath,Xiang Li,Claudia Mondragon,Dawn E. Post,Ming Chen,Anita Hryniewicz-Jankowska,Tiffany Caza,Julie R. White,Vladimir A. Kuznetsov,Heidi Hehnly,Rakesh Khanna,Stephanie Gleicher,Tamara Jamaspishvili,David M. Berman,Fan Zhang,Sonia H.Y. Kung,Ladan Fazli,Gennady Bratslavsky,Pier Paolo Pandolfi,Leszek Kotula

Abi1 loss drives prostate tumorigenesis through activation of EMT and noncanonical WNT signaling.

2019

280Background: Prostate cancer is characterized by heterogeneity of mechanisms which are poorly understood but pointing to epithelial plasticity as the key mechanism in progression to metastatic di...

Keywords:

Prostate
Wnt signaling pathway
Pathology
ABI1
Cancer research
Carcinogenesis
Medicine
epithelial plasticity
Prostate cancer

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