[The microbiological monitoring as a basis of epidemiological control and anti-microbial therapy in conditions of multi-type hospital.]

: The study was carried out to investigate features of microbiota and resistance to antibiotics of agents isolated from bio-material of patients in the conditions of multi-type hospital. The microbiological analysis was applied to 6148 samples using optimal set of corresponding techniques (classical tests, chromogenic mediums, immune serological, Maldi-Tof mass spectrometry). The resistance to antibiotics was established by using disk diffusion test (EUCAST 2016, Adagio analyzer). The leading role in etiology of pyoinflammatory processes belongs to E. coli, coagulase-negative staphylococci, enterococci, C. albicans. In the department of contaminated surgery among leaders are S. aureus, opportunistic enterobacteria, hemolytic streptococci, non-fermentative gram-negative microorganisms. In the department of traumatology and orthopedics first place was for representatives of enterobacteria family headed by E. coli, then follows S. aureus and after that other types of microorganisms. The main representatives of microorganisms, isolated from patients of the department of anesthesiology and reanimation, occurred blue pus bacillus, S.aureus, Klebsiella. In the department of therapy first place was for pneumoccocus and yeast-like fungi genus Candida. The resistance to antibiotics of main microflora differs depending on perspective of profile departments. It is extremely important to examine accurately for detection of agent of disease and to establish sensitivity to antibiotics of various groups.