A versatile protocol for the preparation of substituted 1- and 2-naphthyl piperazines from aminonaphthols

Ana B. Bueno,Claire June Flynn,Jeremy Gilmore,Alicia Marcos,Carlos Montero,Warren J. Porter,Andrew C. Williams

A versatile protocol for the preparation of substituted 1- and 2-naphthyl piperazines from aminonaphthols

2005

Ana B. Bueno
Claire June Flynn
Jeremy Gilmore
Alicia Marcos
Carlos Montero
Warren J. Porter
Andrew C. Williams

Aminonaphthols are easily transformed into a variety of 1- and 2-naphthyl piperazines using a sequence of diazotization, iodide substitution and Pd(0) catalyzed coupling reactions.

Keywords:

Iodide
Coupling reaction
Catalysis
Organic chemistry
Chemistry

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