Synthesis and Bioactivities of Novel N-(4-(2-Aryloxythiazol-5-yl)but-3-yn-2-yl)benzamides

A series of novel N-(4-(2-aryloxythiazol-5-yl)but-3-yn-2-yl)benzamide derivatives were designed and synthesized. Their structures were identified by 1H NMR and elemental analyses. Preliminary bioassays indicated that some title compounds provided >80% control of Sclerotinia sclerotiorum at 50 µg/mL and >70% herbicidal activities against B. campestris at 100 µg/mL. Their structure-activities relationships were also discussed.