5‐Hydroxytryptamine and Other Amines in the Lungs

The sections in this article are: 1 5-Hydroxytryptamine Uptake 1.1 Characterization of Uptake Process 1.2 Localization of Uptake Process 1.3 Monoamine Oxidases of Pulmonary Endothelial Cells 1.4 Pharmacological Inhibition of Uptake Process 1.5 Efflux of Accumulated 5-Hydroxytryptamine 1.6 Uptake in Isolated and Cultured Endothelial Cells 1.7 Uptake and Platelet-Lung Relationships 1.8 Uptake by the Lung and Pharmacological Action of 5-Hydroxytryptamine on Pulmonary Circulation 2 Norepinephrine Uptake 2.1 Characterization of Uptake Process 2.2 Localization of Uptake Process 2.3 l-Norepinephrine Uptake by Isolated Endothelial Cells 2.4 l-Norepinephrine Uptake by the Lung: Uptake 1 (Neuronal) or Uptake 2 (Extraneuronal) 3 Effects of Experimental and Clinical Conditions on 5-Hydroxytryptamine and Norepinephrine Uptake 3.1 Experimental Conditions 3.2 Application to Human Clinical Problems 4 Other Naturally Occurring Catecholamines 4.1 β-Phenylethylamine 4.2 Dopamine 4.3 Epinephrine 4.4 Octopamine 5 Sympathomimetic Drugs 5.1 Metaraminol 5.2 Isoprenaline 5.3 Mescaline 6 Histamine 7 Uptake of Basic Amines by the Lung 8 Conclusion