Covid-19: Pfizer vaccine provides 90% protection against infection in children aged 5-11, study finds.
2021
Children aged 5-11 who are given a low dose of the Pfizer-BioNTech mRNA vaccine produced good antibody responses with no reported serious adverse effects, researchers have shown.
The research, published in the New England Journal of Medicine ,1 found that a 10 μg dose—a third of the adult dose—gave around 90% protection from covid-19. However, the study included only 2268 participants and so may not be large enough to detect very rare adverse events.
After a phase I study suggested that the optimum dose for this age group was 10 μg of the Pfizer-BioNTech vaccine, 1517 children were randomly assigned to receive this dose, while 751 children received a placebo. A second dose was administered 21 days …
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