First in-human study of in vivo imaging of ex vivo labeled CAR T cells with dual PET-MR.

Ritu Singla,Dominic Wall,Samuel R. Anderson,Nicholas Zia,James C. Korte,Lucy Kravets,Gerard McKiernan,Jeanne Butler,Amanda Gammilonghi,Jyoti Arora,Ben Solomon,Rodney J. Hicks,Timothy Cain,Phillip K. Darcy,Carleen Cullinane,Paul J. Neeson,Rajesh Ramanathan,Ravi Shukla,Vipul Bansal,Simon J. Harrison

First in-human study of in vivo imaging of ex vivo labeled CAR T cells with dual PET-MR.

2020

3557Background: This is a first in human in-vivo biodistribution of ex-vivo labelled CAR T cells assessed in a cohort of patients. Cells were labelled with novel Cu-64 labelled superparamagnetic ir...

Keywords:

first in human
Preclinical imaging
car t cells
Pathology
Ex vivo
Medicine

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