The predictive study of early renal damage in essential hypertension by Doppler ultrasound renal blood flow measurement

Objective To evaluate the value of ultrasound Doppler renal blood flow measurement in diagnosing early renal damage of hypertension.Methods Sixty patients with hypertension and twenty normotensive subjects were included in the study. They were classified into three groups according to β 2 MG contents in blood or urine and urinary albumin excretion rate (UAER).Renal blood flow was measured all in patients by Doppler ultrasound. Results The earliest abnormal of renal blood flow occured in hypertensives included that the end diastolic velocity (V d) of interlobar artery was decreased and the acceleration time (AT) of segmental and interlobar artery was increased.Peak velocity in systole(V s) and V d decreased and pulsed index (PI) and resistance index (RI) inceased in segmental and interlobar artery of all hypertensives with early renal damage.Conclusions Doppler Ultrasound renal blood flow measurement may be clinically useful in the noninvasive evaluation of early renal damage of hypertension.