Role of glutathione S-transferase (GSTM1) gene polymorphism in development of uterine fibroids

Emerson de Oliveira,Rodrigo de Aquino Castro,Mariano Tamura Vieira Gomes,Ismael Dale Cotrim Guerreiro da Silva,Edmund Chada Baracat,Geraldo Rodrigues de Lima,Marair Gracio Ferreira Sartori,Manoel João Batista Castello Girão

Role of glutathione S-transferase (GSTM1) gene polymorphism in development of uterine fibroids

2009

Emerson de Oliveira
Rodrigo de Aquino Castro
Mariano Tamura Vieira Gomes
Ismael Dale Cotrim Guerreiro da Silva
Edmund Chada Baracat
Geraldo Rodrigues de Lima
Marair Gracio Ferreira Sartori
Manoel João Batista Castello Girão

Glutathione S-transferase (GSTM1) plays an important role in the excretion of catechol estrogens and is therefore a candidate marker for fibroids. However, this case–control study demonstrated no association between GSTM1 polymorphism and the risk of leiomyoma in Brazilian women.

Keywords:

Glutathione S-transferase
Leiomyoma
Glutathione
Uterine fibroids
Gene polymorphism
Excretion
Polymorphism (computer science)
Endocrinology
GSTM1 Gene
Medicine
Internal medicine
uterine leiomyoma

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