The structural properties of the saliva in the modelling of a cariogenic situation

: A cariogenic situation was modeled by soft acidification by hydrochloric acid in vitro in mixed salivary pool of 10 subjects aged 16-18, and the values of pH and active concentration of sodium ions, optic density, and concentration of inorganic phosphorus were studied. Soft acidification of human mixed saliva was found to result in its structural disorders. The saliva of subjects with negligible caries was more stable to unfavorable exposure than mixed saliva of subjects with a higher CFL index. Experiments showed that pH of 6.2 is the critical value causing evident destruction of the saliva and reducing its mineralizing potential. These data may be used in studies of the molecular mechanisms of caries development.