Temporal Lobe Atrophy and White Matter Lesions are Related to Major Depression Over 5 Years in the Elderly Running title: Brain Changes Related to Major Depression in the Elderly

Department of Neurological and Psychiatric Sciences, University of Florence, Italy Correspondence: Dr PJ Olesen, Neuropsychiatric Epidemiology Unit, Wallinsgatan 6, 43141 Molndal, Sweden; Tel: +46 31 3438642, Fax: +46 31 7760403, E-mail: Pernille.olesen@neuro.gu.se . Word Count Abstract: 249 Word Count Text: introduction: 444; materials/methods 1491 Figures: 0 Tables: 2 Supplementary Material: 0