Antiproteinuric Effect of Chemokine C-C Motif Ligand 2 Inhibition in Subjects with Acute Proliferative Lupus Nephritis

Alessandro Ble,Marta Mosca,Giorgio Di Loreto,Angelo Guglielmotti,Giuseppe Biondi,Stefano Bombardieri,Giuseppe Remuzzi,Piero Ruggenenti

Antiproteinuric Effect of Chemokine C-C Motif Ligand 2 Inhibition in Subjects with Acute Proliferative Lupus Nephritis

2011

Alessandro Ble
Marta Mosca
Giorgio Di Loreto
Angelo Guglielmotti
Giuseppe Biondi
Stefano Bombardieri
Giuseppe Remuzzi
Piero Ruggenenti

Background/Aims: To test the role of chemokine C-C motif ligand 2 (CCL2) in the pathogenesis of lupus nephritis (LN), we evaluated the effects of CCL2 inhibition by bindarit therapy

Keywords:

Renal function
Albuminuria
CCL2
Lupus nephritis
Pathogenesis
Chemokine
Endocrinology
Medicine
Internal medicine
Diabetes mellitus
Immunology
Ligand

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