Amoxicillin Resides in Milk of Holstein Cows With Double or Triple Intramammary Administration of Amoxicillin-Potassium Clavulanate

The aim of this study was to determine dif- ferences in residue elimination of amoxicil- lin (AMX) in cows milk, after intramam- mary administration of a pharmaceutical preparation of AMX plus potassium clavula- nate (CLV), either in healthy or in spontane- ous cases of clinical mastitis, and follow- ing label instructions or administering the preparation in an extra-label manner. Twelve lactating healthy Holstein/Friesan cows in production and negative to clinical mastitis were treated with a commercial brand of