Boala Kawasaki – actualităţi în sprijinul practicianului pediatru

Kawasaki disease is an acute systemic vasculitis, sometimes still perceived as an exotic disease, consequently its diag­nostic is overlooked or delayed. Although the first des­crip­tion of the disease was made in Japan 50 years ago, the diagnosis remains based on clinical crite­ria. The etio­lo­gy is unknown, but the current ac­cep­ted theory is that an infectious trigger initiates a par­ti­cular immune res­ponse in children with a genetic predisposition for this disease. The main complication of Kawasaki disease is coro­nary aneurysm. The prompt administration of high doses of im­mu­no­glo­bu­lins is essential to reduce the cardiovascular com­pli­cations.