Cryptogenic mechanism in ischaemic stroke patients is a predictor of 5-year survival: A population-based study

IntroductionThe present study sought to identify factors affecting mortality beyond 28 days in ischaemic stroke patients with whatever ischaemic mechanism.Patients and methodsA prospective population-based registry was set up in Brest County, Brittany, France. Demographic data, clinical presentation, vascular risk factors and mortality were collected from January 2008 to December 2012. At “home without help” was used as a surrogate marker for low Rankin (0–1) at discharge from the hospital. IS was classified on the TOAST classification. Overall mortality was calculated using the Kaplan–Meier method. Multivariate analysis of mortality beyond 28 days was implemented, using a Cox model, on significant risk factors identified on univariate analysis.ResultsAbout 3024 IS cases were followed up beyond 28 days. Overall mortality beyond 28 days was 38.49% at 60 months. On multivariate analysis, age (10 years: HR = 1.84; [1.66–2.02]), coronary artery disease (HR = 1.28; [1.05–1.56]), cardiac arrhythmia (HR = 1.36; ...