Preparation method and application of nanometer particles of taxane drugs

The invention discloses a preparation method of a nanometer preparation of taxane drugs. The nanometer particles prepared by utilizing an emulsion diffusion method comprise the taxane drugs, copolymer carrier materials and emulgators. The preparation method comprises the steps of: dissolving the taxane drugs and the copolymer carrier materials into an organic phase mutually soluble with water, then dropwise adding the solution into a mixed solution of water in which the emulgators are dissolved and ethanol, stirring and mixing to form emulsion, and forming nanometer particles after removing organic solvents and solidifying. According to the nanometer particles prepared by utilizing the preparation method, the particle sizes are very uniform, the average particle size is 80-120 nm, the encapsulation efficiency is high, the stability is good, the preparation process is simple and controllable, and the scaled-up production is liable. The nanometer particles prepared by utilizing the preparation method can be applied to the treatment of malignant tumors and have obvious tumor inhibition effects.