Abstract 14884: Frailty Status and Transcatheter Aortic Valve Replacement Outcome Regardless of Society of Thoracic Surgery Risk Score

Introduction: Society of Thoracic surgery (STS) risk score is used to determine transcatheter aortic valve replacement (TAVR) procedure risk. We sought to study the incremental improvement of STS risk score using frailty status in predicting one-year outcome after TAVR Hypothesis: Frail patients have higher mortality after TAVR beyond STS risk score Methods: The study population included 544 consecutive TAVR patients who had full frailty assessment and STS score calculation at time of procedure. Frailty defined by the presence of any 3 of the following 5 criteria: algorithm defined grip strength and 5-meter walking tests, BMI <20kg/m2, Katz ADL ≤4/6, serum Albumin<3.5g/dL. Multivariable logistic analysis of 30-day and 1-year mortality was performed using logistic regression model that comprised the STS risk score model as a single variable Results: Based on frailty definition, 242 patients were frail, while 302 patients were not frail. STS score was higher in frail group compared to non-frail group (mean ...