Isothiourea‐catalyzed functionalization of pyrrolyl‐ and indolylacetic acid: enantioselective synthesis of dihydropyridinones and one‐pot synthesis of pyridinones

Shuyue Zhang,Lucas Bacheley,Claire M. Young,Daniel Graham Stark,Timothy J. C. ORiordan,Alexandra M. Z. Slawin,Andrew D. Smith

Isothiourea‐catalyzed functionalization of pyrrolyl‐ and indolylacetic acid: enantioselective synthesis of dihydropyridinones and one‐pot synthesis of pyridinones

2020

Shuyue Zhang
Lucas Bacheley
Claire M. Young
Daniel Graham Stark
Timothy J. C. ORiordan
Alexandra M. Z. Slawin
Andrew D. Smith

Funding: ERC under the European Union's Seventh Framework Programme (FP7/2007–2013) / ERC grant agreement no 279850. We thank Syngenta and EPSRC grant No. EP/K503162/1 (DGS), ADS thanks the Royal Society for a Wolfson Research Merit Award.

Keywords:

Heterocycle synthesis
Catalysis
Organocatalysis
Chemistry
Organic chemistry
Enantioselective synthesis
One-pot synthesis
Surface modification

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