The Synthesis of Distamycin Analog Containing Phosphonyl Group

Yong Ye,Shang-Bin Zhong,Ruo-yu Liu,Li-Feng Cao,Cun-Jiang Liu,Junliang Yang,Yu-Fen Zhao

The Synthesis of Distamycin Analog Containing Phosphonyl Group

2008

Yong Ye
Shang-Bin Zhong
Ruo-yu Liu
Li-Feng Cao
Cun-Jiang Liu
Junliang Yang
Yu-Fen Zhao

In order to obtain high biological activity compound, a series of distamycin analog containing phosphonyl group were synthesized by chloroform reaction and coupling reaction using DCC/HOBT as promoting additives.

Keywords:

Distamycin
Inorganic chemistry
DNA
Polyamide
Organic chemistry
Coupling reaction
Chemistry
Chloroform
Biological activity

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