Синтез и местноанестезирующая активность новых производных ароилпировиноградных кислот
2014
Chlorides of N-{2-[(1Z)-1-{[(2,6-dimethylphenyl)amino]carbonyl}-3-oxo-3-arylprop-1-en-1-yl)amino]ethyl}-N,N-dimethyl-1-oxoethanaminium were synthesized by acylation of enaminoamides of arylpyruvic acids. The local anesthetic properties of the synthesized compounds were investigated. Some of these compounds exhibited significant local anesthetic activity.
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