The study of prevalence and antimicrobial susceptibility of bacterial isolated from urinary tract in outpatients admitted to Shohda hospital, Gonbad

Introduction:Urinary tract infection is the most common bacterial infection affecting human health. Early diagnosis, proper treatment and appropriate follow-up the patient can result in significant reduction in symptoms. Increase of drug resistance need for evaluation of antibiotic resistance patterns had revealed to improve empirical treatment. The purpose of this study is to identify common bacterial agents and evaluate their drug resistance pattern in Gonbad. Methods: This cross-sectional study was conducted in outpatients admitted to Shohada hospital, Gonbad during a six-month period from February 2014 to July 2015. Identification of bacterial based on microbiological and biochemical tests was performed. Disk diffusion method performed on Mueller Hinton Agar was used to determine antibacterial activity of antibiotics in accordance with Clinical and Laboratory Standards Institute (2015) guidelines. Results: Of 138 outpatients,the most common bacteria isolated from urine samples were including Escherichia coli 94 (68.11), Klebsiella pneumoniae 16 (11.59), Staphylococcus aureus 16 (11.59) and Enterococus species 10 (7.24) respectively. The most of isolated bacteria were susceptible to nitrofurantoin 65.14 and high resistance rates were observed for ampicillin, cotrimoxazole and cephalotin 56.70, 43.76 and 44.82, respectively. Conclusion: Theidentified bacteria showed much lower rates of resistance to ciprofloxacin with prevalence rate of 47.27. It is also recommended to lower ampicillin and co-trimoxazole use for initial treatment of urinary tract infections as high resistance.