Application of Porous Microspheres in the Field of Medicine and Pharmacy

As a new drug dosage form,porous microsphere has been widely used in the development of new formulations and the transformation of new dosage form of porous microsphers have rich resources,such as natural polymer materials,inorganic materials, polymer molecules etc.As a new carrier for drug controlled/sustained release,microspheres have numerous advantages as follows: protecting the drug from degradation,having special affinity to some cells or tissues,controling the release rate and prolonging the function time of the drug,reducing the drug toxicity and decreasing the drug amount.It also can be used for drug's target in some specific organs and tissues.What is more,porous microspheres have a rather big surface area and pore volume,which makes them easy for drug adsorbed on the surface or trapped in the pore.Thus drugs can be made into immediate-release or sustained-release formulations according to body needs.The review deals with the current development of several typical porous microspheres and their applications in biomedical field.