Regio‐ and Stereoselective Synthesis of Novel Spiropyrrolidines Through 1,3‐Dipolar Cycloaddition Reactions of Azomethine Ylides and 2‐Styrylquinazolin‐4(3H)‐ones.

Ram Awatar Maurya,Ranjita Nayak,Chada Narsimha Reddy,Jeevak Sopanrao Kapure,Jagadeesh Babu Nanubolu,Kiran Kumar Singarapu,M. Ajitha,Ahmed Kamal

Regio‐ and Stereoselective Synthesis of Novel Spiropyrrolidines Through 1,3‐Dipolar Cycloaddition Reactions of Azomethine Ylides and 2‐Styrylquinazolin‐4(3H)‐ones.

2015

Ram Awatar Maurya
Ranjita Nayak
Chada Narsimha Reddy
Jeevak Sopanrao Kapure
Jagadeesh Babu Nanubolu
Kiran Kumar Singarapu
M. Ajitha
Ahmed Kamal

Title compounds [(IV) and (VI)] are synthesized through 1,3-dipolar cycloaddition of styrylquinazolinones (III) with azomethine ylides generated in situ from isatin (I) or acenaphthoquinone (V), resp., with L-proline (II).

Keywords:

Cycloaddition
1,3-Dipolar cycloaddition
Acenaphthoquinone
Isatin
Chemistry
Stereoselectivity
Organic chemistry

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