Sevoflurane protects ventricular myocytes against oxidative stress-induced cellular Ca2+ overload and hypercontracture.

Background:Oxidative stress is implicated in pathogenesis of cardiac reperfusion injury, characterized by cellular Ca2+ overload and hypercontracture. Volatile anesthetics protect the heart against reperfusion injury primarily by attenuating Ca2+ overload. This study investigated electrophysiologica