Abstract 8559: Efficacy of Implantable Cardiac Defibrillators for the Prevention of Sudden Cardiac Death in Patients with Cardiac Sarcoidosis

Introduction Patients with cardiac sarcoidosis (CS) are at increased risk for sudden death from ventricular arrhythmias. There is little evidence regarding the efficacy and safety of implantable cardiac defibrillators (ICDs) in this population. Hypothesis Data on demographic, clinical, and ICD intervention history was retrospectively collected on 138 CS patients with ICDs from 11 academic centers throughout the U.S., Canada, and India. We hypothesized that patients with CS would have a high incidence of appropriate ICD therapies. Results Sixty-two of 138 CS patients (44.92%) had an appropriate ICD therapy (ATP or shock) with 39 patients (28.3%) receiving 5 or more therapies (Figure). Forty-eight of 131 patients (36.64%) received an appropriate shock. Thirty-seven of 136 patients (27.21%) had an inappropriate shock. The incidence of appropriate therapy (ATP or shock) was 10.4%/year and the incidence of appropriate shock was 8.5%/year. Twenty-two patients (15.9%) experienced an adverse event, the most commo...