Abstract 11051: A Small-Molecule Factor XIa Inhibitor (BMS-962212) Provides Robust Antithrombotic Activity in Non-Human Primate Model of Arterial Thrombosis With Low Bleeding

Introduction: Factor XIa (FXIa) is a novel target for safer antithrombotic therapy. BMS-962212 is a potent (Ki = 0.7nM), selective, reversible, active-site inhibitor of human FXIa designed for pare...