A cross-national study of augmentation of cholinesterase inhibitors with memantine in Alzheimer's disease

fields have been discovered. Methods: Subchronic effect of a weak combined magnetic field (MF), produced by superimposing a constant component (region mT) and an alternating MF of (0.1 mT) which was the sum of signals of frequencies region Hz, was studied in olfactory bulbectomized and transgenic B6aC3-Tg (APPswe, PSEN1DeltaE9) 85DBO/J mice, which were used as animal models of sporadic and heritable Alzheimer’s disease accordingly. Exposure to the MFs induced the decrease of Ab level in bulbectomized mice and reduced the number of Ab plaques in the cortex and hippocampus. Results: Positive results were obtained in volunteers with Alzheimer’s desease.We have developed several types of equipment for correction and treatment of their condition. Conclusions: We expect that numerous positive pieces of evidence both in animal experience and with humans will be of enormous importance for those suffering from different stages of Alzheimer’s desease all over the world.