İNTRAVENÖZ İMMÜNGLOBULİN TEDAVİSİ İLE HIZLI İYİLEŞME GÖSTEREN BİR MİLLER FİSHER SENDROMU OLGUSU

Miller-Fisher Syndrome is a rare and benign form of Guillain-Barre Syndrome and characterized by the acute onset of ophthalmoplegia, areflexia and ataxia. In our case, 28 year old male patient applied to our clinics with the complaints of double vision and gait imbalance. During the medical examination, bilateral total ophthalmoplegia, facial diplegia, truncal ataxia and areflexia were noticed. The results of the routine analyses of blood parameters, cranial computed tomography (CT) and magnetic resonance imaging (MRI) were normal. In the examination of cerebrospinal fluid, albuminocytologik dissociation was determined. Electromyography (EMG) results indicated the presence of sensorial neuropathy. The case was diagnosed as Miller-Fisher Syndrome and administered with intravenous immunglobuin (IVIG) at the dose of 400 mg/kg/day, for five days. On the third day of treatment, clinical symptoms stated to be ameliorated and on the 7 th day of the treatment, all the clinical symptom disappeared. EMG results obtained on 14 th day of treatment indicated a complete healing of the case.The results of this case indicate that IVIG treatment, compared to classical aproaches, seems a more effective and indespensable treatment option.