Effect of Atorvastatin on Serum Visfatin Levels in Treatment of Acute Cerebral Infarction
2012
Objective To explore the effect of atorvastatin on serum visfatin level of patients with acute cerebral infarction.Methods 80 cases with acute cerebral infarction were randomly divided into the observation group(n=40)and the control group(n=40),40 patients without cerebrovascular disease of the same period were chosen as normal group,serum visfatin level of the observation group and normal group were compared to discuss the risk factor of the indicator of acute cerebral infarction;the observation group and the control group were given atorvastatin combined with conventional treatment and conventional therapy respectively,serum visfatin level of the two groups were compared.Results The visfatin levels of patients in the observation group were significantly higher than those in the normal group,with statistically significant difference(P0.01).Logistic regression analysis showed that the serum visfatin level is a risk factor for acute cerebral infarction.The therapeutic effect of the observation group was significantly better than the control group(P0.01).Conclusion Atorvastatin can effectively reduce the serum visfatin levels with good therapeutic effect.
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