UCP1-independent glucose lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia

Petr Zouhar,Günaj Rakipovski,Muhammad Hamza Bokhari,Oliver Busby,Johan F. Paulsson,Kilian W. Conde-Frieboes,Johannes Josef Fels,Kirsten Raun,Birgitte Andersen,Barbara Cannon,Jan Nedergaard

UCP1-independent glucose lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia

2019

Petr Zouhar
Günaj Rakipovski
Muhammad Hamza Bokhari
Oliver Busby
Johan F. Paulsson
Kilian W. Conde-Frieboes
Johannes Josef Fels
Kirsten Raun
Birgitte Andersen
Barbara Cannon
Jan Nedergaard

The possibility to use leptin therapeutically for lowering glucose levels in type 1 diabetic patients has attracted interest. However, earlier animal models of type 1 diabetes are severely cataboli...

Keywords:

Type 1 diabetes
Leptin
Biology
Diabetes mellitus
Internal medicine
Endocrinology
Glucagon
in patient
glucose lowering
Thermogenin

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