Abstract 12241: Delayed Time to Intrinsicoid Deflection on the 12-Lead ECG and Myocardial Scarring From the Multi-Ethnic Study of Atherosclerosis

Background: Delayed time to intrinsicoid deflection (DID) is an ECG finding associated heart failure (HF) independent of left ventricular hypertrophy (LVH). Myocardial scarring has been postulated as an additional cause for the development DID and may influence the adverse findings associated with this ECG marker beyond left ventricular mass (LVM). In this study, we further characterized the relationship of DID with the presence of myocardial scarring as detected on cardiac MRI (CMRI). Methods: 1708 individuals without clinical cardiovascular disease or ventricular conduction delays (QRS >120 ms) from the Multi-Ethnic Study of Atherosclerosis were studied over an average of 9.5 years. An adjudication committee determined incident HF and the time to the development of HF during the follow up period. CMRI studies were performed using gadolinium contrast to assess for the presence and percentage of myocardial scar. Intrinsicoid deflection was automatically measured in leads V5and V6 from 12-lead ECGs, and DI...