Assessing The Consistency Of Absolute Cardiovascular Risk Prediction And Relative Risk Reduction In Type-2 Diabetes Mellitus

• Accurate estimation of baseline cardiovascular (CV) risk and relative risk reduction (RRR) is crucial to ensure that economic evaluations of new health technologies for the treatment of type 2 diabetes (T2DM) are robust. • Many economic models (such as the IMS CORE Diabetes Model [1]) use risk equations (RE) derived from UKPDS and concerns persist regarding their validity; particularly as new equations are published. • The potential choice of risk equations is large; a recent review [2] identified twelve cardiovascular disease risk equations derived from cohorts with T2DM. • The objective of this study was to compare the consistency of predicted CV risk using RE derived from various T2DM populations. Objectives