Abstract 21405: Dynamic Enhancement Pattern is Different Between Unstable and Stable Coronary Plaque: Analysis With 320-Row Area Detector Computed Tomography

Introduction: Intraplaque neovascularization is a marker of unstable coronary plaque. We investigated a difference in dynamic enhancement pattern of coronary plaque between stable and unstable angina pectoris, using 320-row area detector computed tomography (CT), which enables whole-heart volumetric acquisition in a single gantry rotation. Hypothesis & Methods: We analyzed 106 coronary plaque segments in 38 patients (mean age 69.8±8.3 years, 32 male) with angina pectoris (13 stable, 25 unstable) who underwent coronary CT and percutaneous coronary intervention (PCI). Coronary plaques were evaluated using 320-row area detector CT with and without contrast enhancement. Culprit plaques (PCI target) of unstable patients were defined as unstable plaque(n=35), whereas culprit plaques of stable patients and non-culprit plaque were defined as stable plaque(n=71). Coronary plaque without contrast enhancement, corresponding to the plaque detected by contrast enhanced CT, was identified using unique calcification as ...