A comparative study of narrow-band imaging （NBI） with routine endoscopy and NBI with magnifying endoscopy for the diagnosis of colorectal neoplasia

Objective To compare the diagnostic efficacies of narrow-band imaging （NBI） in distinguishing neoplastic from non-neoplastic colorectal lesions with routine endoscopy and with magnifying endoscopy. Methods Patients with colorectal lesions detected by NBI from September 2008 to February 2010 were enrolled in the study. These lesions were classified by pit pattern and capillary pattern, which was then assessed by reference to histopathology. Results A total of 100 patients with colorectal lesions were enrolled, and the lesions were observed by NBI with ordinary endoscopy （n =64） and NBI with magnifying endoscopy （n =36）, respectively, and 7 cases （5 in NBI with ordinary endoscopy and 2 in NBI with magnifying endoscopy） which did not meet the diagnostic criteria were excluded. The overall diagnostic accuracy of NBI endoscopy in distinguishing neoplastic from non-neoplastic colorectal lesions was 91.4% （ 85/93 ）, in which NBI with ordinary endoscopy and magnifying endoscopy was 89. 8% （53/59） and 94. 1% （32/34）,respectively, with both significantly higher than that of conventional colonoscopy reported in the literature （79. 1% ） （P 〈 0. 05 ）. However, no significant difference was detected between 2 methods （ P 〉 0. 05 ）.Conclusion Similar with NBI magnifying endoscopy, NBI endoscopy without high magnification may also be useful to distinguish neoplastic from non-neoplastic colorectal lesions. Key words: Colonic neoplasns; Endoscopy ; Narrow-band imaging;  Diagnosis