Degraded diet induced thermogenesis induced by 20 days of 6 degrees head down bed rest and effect of resistance training.

: In the 21st century, our dream of living in a space will finally become reality. To understand the effects of microgravity on energy expenditure and possible countermeasure against them is important to maintain human health in space. Diet Induced Thermogenesis (DIT) is an increase in energy expenditure after ingestion of a meal, and accounts for 10% of total daily energy expenditure. Recently, the important role of DIT in regulating obesity is suggested. Basal Energy Expenditure (BEE), on the other hand, is the minimum energy expenditure required to keep on living, and accounts for 60-75% of total energy expenditure. Despite the importance of DIT, no information about DIT in microgravity and possible effects of exercise training is available. Therefore, we aimed to investigate, first, the effects of 20-days of 6 degrees head down tilting bed rest (HDBR) on postabsorptive energy expenditure (PEE), DIT, and BEE. Second, the effects of resistance training during HDBR on DIT and BEE.