Association between Delayed Lactogenesis II and Early Milk Volume among Mothers of Preterm Infants

Abstract Purpose This study aimed to evaluate the effect of delayed lactogenesis Ⅱ on early milk volume in mothers expressing milk for their preterm infants. Methods 142 mothers with preterm infants participated in a longitudinal cohort study, the milk volumes over 14 days postpartum between mothers with delayed lactogenesis Ⅱ (≥72 hours) and mothers with non-delayed lactogenesis Ⅱ( Results The prevalence of delayed lactogenesisⅡ among mothers of preterm infants was 36.0% (36/100). There existed negative correlations between the onset of lactogenesis Ⅱ and the daily milk volumes( r s = −0.525∼−0.354， p= .002 ∼ p p = .002 ∼ p Conclusion Delayed lactogenesis Ⅱ was associated with lower milk volume in early postpartum period. Women who were at risk for delayed lactogenesis Ⅱ need targeted interventions and additional support during pregnancy and postpartum.