Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis

Yan Ye,Mei Liu,Longhai Tang,Fang Du,Yuanhua Liu,Pei Hao,Qiong Fu,Qiang Guo,Qingran Yan,Xiaoming Zhang,Chunde Bao

Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis

2019

Yan Ye
Mei Liu
Longhai Tang
Fang Du
Yuanhua Liu
Pei Hao
Qiong Fu
Qiang Guo
Qingran Yan
Xiaoming Zhang
Chunde Bao

Background This study aimed to explore the molecular mechanism and clinical relevance of iguratimod in the regulation of human B cell terminal differentiation.

Keywords:

Protein kinase C
Iguratimod
Rheumatology
Immunology
EGR1
Diabetes mellitus
Pharmacology
Internal medicine
Medicine
B cell
Transcription factor
Cell
Cancer research
In vitro
Flow cytometry

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