The role of androgen deprivation therapy on the clinical course of COVID-19 infection in men with prostate cancer.

Vaibhav G. Patel,Xiaobo Zhong,Neil J. Shah,Luis A. Pina Martina,Jessica Hawley,Emily Lin,Benjamin A. Gartrell,Victor Ricardo Adorno Febles,David R. Wise,Qian Qin,George Mellgard,Jones T. Nauseef,David A. Green,Panagiotis J. Vlachostergios,Daniel Kwon,Franklin W. Huang,Bobby Chi-Hung Liaw,Scott T. Tagawa,Michael J. Morris,William Oh

The role of androgen deprivation therapy on the clinical course of COVID-19 infection in men with prostate cancer.

2021

41Background: TMPRSS2, a cell surface protease which is commonly upregulated in prostate cancer (PC) and regulated by androgens, is a necessary component for SARS-CoV2 cellular entry into respirato...

Keywords:

Prostate cancer
Oncology
Downregulation and upregulation
clinical course
Coronavirus disease 2019
Protease
Androgen deprivation therapy
Medicine
TMPRSS2
Internal medicine
Cell

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