Phase I single and multiple dose study to evaluate the safety, tolerability, and pharmacokinetics of BMS-927711 in healthy subjects

Calcitonin gene-related peptide (CGRP) may play a causal role in migraine. Blocking the CGRP receptor may be an effective approach to migraine relief while avoiding the vasoconstrictive effects associated with triptans. BMS-927711 is a potent, selective, CGRP receptor antagonist. The