Pharmacodynamics of romiplostim alone and in combination with pegfilgrastim on acute radiation-induced thrombocytopenia and neutropenia in non-human primates

Karen Wong,Polly Y. Chang,Mark R. Fielden,Anne Marie Downey,Deborah I. Bunin,James Bakke,Janet Gahagen,Lalitha V. Iyer,Sameer Doshi,Wieslaw Wierzbicki,Simon Authier

Pharmacodynamics of romiplostim alone and in combination with pegfilgrastim on acute radiation-induced thrombocytopenia and neutropenia in non-human primates

2019

Karen Wong
Polly Y. Chang
Mark R. Fielden
Anne Marie Downey
Deborah I. Bunin
James Bakke
Janet Gahagen
Lalitha V. Iyer
Sameer Doshi
Wieslaw Wierzbicki
Simon Authier

AbstractPurpose: Evaluation of the pharmacodynamics (PD) and pharmacokinetics (PK) of romiplostim alone and in combination with pegfilgrastim in a non-human primate (NHP) model of acute radiation s...

Keywords:

Molecular biology
Romiplostim
Neutropenia
Biology
Oncology
Pharmacodynamics
Internal medicine
Pegfilgrastim
radiation induced
Pharmacology
Pharmacokinetics

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