Occurrence of myofibroblasts in recurrent Dupuytren's disease: An electron microscopic study

Surgically removed nodules from ten patients with recurrent Dupuytren's disease were studied by electron microscopy. Myofibroblasts were found in eight cases in the active (involutional) stage. The distinctive ultrastructural features were similar to those of the original Dupuytren's disease. We believe that, in addition to other factors, myofibroblasts have a non-specific but important role in the pathology of recurrent Dupuytren's disease.