Swirls and spots: relationship between qualitative and quantitative hematoma heterogeneity, hematoma expansion, and the spot sign

Background Acute intracerebral hemorrhage (ICH) heterogeneity on NCCT, characterized by qualitative and quantitative methods, is predictive of hematoma expansion and mortality however association with the spot sign is not well-described. We sought to validate and determine the association between qualitative and quantitative hematoma heterogeneity with expansion and the spot sign, respectively.